Manda Koso’s possibilities seen from a scientific point of view.
Published academic themes and titles.
Cancers
Cancers/Anti-oxidation
Stress
Alcohol consumption
Sexual function
Infectious illness
Menopause/Osteoporosis
Anti-oxidation/Anti-aging
Formation of blood clot
Clinical symptoms/Drug toxicity
Radiation damages
Growth/Feedstuff
Anti-oxidation
[Title]
Free Radical Scavenging Action of MANDA(Japanese)
[Journal] The Clinical Report Vol.28 No.2, 1994
[Author] Kawai, et al.
[Target] test tube
[Title]
Effects of a fermented vegetable product on hemolysis and lipid preoxidation of Japanese flounder erythrocytes
[Journal] Fisheris Science 68, 2002
[Author] Ashida, et al.
[Target] flounder, erythrocytes
[Title]
The dietary effects of a fermented vegetable product on glutathioone peroxidase activity and lipid peroxidation of Japanese flounder Paralichthys olivaceus
[Journal] Fisheris Science 72, 2006
[Author] Ashida, et al.
[Target] flounder, serum, liver
Cancers
[Title]
Antitumor and Immunopotentiating Effects of Manda Enzyme
[Journal] Natural Product Sciences 2(1), 1996
[Author] Hwang, et al.
[Target] mouse, whole body
[Title]
Postoperative Effect of Manda on NK Cell Activity in Cancer Patients(Japanese)
[Journal] Biotherapy 13(7), 1999
[Author] Yamamoto, et al.
[Target] human, whole body
[Title]
Inhibitory Effects or Fermentive Foods Prepared from Plant Materials on Tumor Growth and Metastasis to Lung (Japanese)
[Journal] The Japanese Journal of Constitutional Medicine Vol.61 No.1/2, 1999
[Author] Kimura, et al.
[Target] mouse, whole body
[Title]
Inhibition of Human Breast Cancer Cell Growth and Enzymatic Activity by a Fermented Nutraceutical: An in Vitro and in Vivo Study
[Journal] Annuals of the New York Academy of Sciences 1155, 2009
[Author] Marotta, et al.
[Target] mouse, breast cancer
Cancers/Anti-oxidation
[Title]
ANTIOXIDANT AND ANTITUMOR EFFECTS OF MANDA
[Journal] Biochemical Archives Vol.14, 1998
[Author] Kim, et al.
[Target] mouse, liver, lung
[Title]
IN VITRO ANTIOXIDANT AND ANTICANCER ACTIVITIES OF EXTRACTS FROM A FERMENTED FOOD
[Journal] Journal of Food Biochemistry 27, 2003
[Author] Kim, et al.
[Target] test tube
Stress
[Title]
Manda Suppresses Emotional Stress-Induced Stomach Ulcers in Rats
[Journal] International Journal of Stress Management Vol.4 No.1, 1997
[Author] Kawai, et al.
[Target] rats, stomach ulcer
[Title]
Effect of a dietary fermented vegetable product on the heat shock response of Japanese flounder Paralichthys olivaceus
[Journal] Fisheris Science 75, 2009
[Author] Ashida, et al.
[Target] flounder, stress from outside the body
Alcohol consumption
[Title]
Inhibitory effect of MANDA on blood acetaldehyde concentration after alcohol administration (Japanese)
[Journal] Progress in Medicine Vol.18 No.7, 1998
[Author] Kawai, et al.
[Target] human, liver
Sexual function
[Title]
Experimental and Clinical Studies on the Effects of Manda Enzyme on Male Sexual Functions(Japanese)
[Journal] Journal of the Japanese Society of Impotence Research Vol.4 No.1/2, 1989
[Author] Koshido, et al.
[Target] human, sexual dysfunction
Infectious illness
[Title]
Immunostimulatory effects of fermented vegetable product on the non-specific immunity of Japanese flounder Paralichthys olivaceus
[Journal] Fisheris Science 71, 2005
[Author] Ashida, et al.
[Target] flounder, whole body
Menopause/Osteoporosis
[Title]
Effects of a Fermented Vegetable Product on Fat Deposition and Bone Metabolism in Ovariectomized Rats
[Journal] Journal of Nutritional Science and Vitaminology 50, 2004
[Author] Shimada, et al.
[Target] rats, weight gain, body fat
Anti-oxidation/Anti-aging
[Title]
MANDA SCAVENGES FREE RADICALS AND INHIBITS LIPID PEROXIDATION IN IRON-INDUCED EPILEPTIC FOCUS IN RATS
[Journal] Food and Free Radicals, 1997
[Author] Kawai, et al.
[Target] rats, cranial nerve
[Title]
Manda, a Fermented Natural Food, Suppresses Lipid Peroxidation in the Senescent Rat Brain
[Journal] Neurochemical Research Vol.23 No.4, 1998
[Author] Kawai, et al.
[Target] rats, brain
Formation of blood clot
[Title]
Isolation and Partial Characterization of a Polysaccharide with Antithrombin Activity against Blood Coagulation in Manda, a Fermented Natural Food
[Journal] Agricultural Chemistry and Biotechnology 43(4), 2000
[Author] Kim, et al.
[Target] test tube, thrombus
Clinical symptoms/Drug toxicity
[Title]
Experimental and Clinical Studies of Manda Enzyme on General Complaints of Hemodialysed Patients (Japanese)
[Journal] The Clinical Report Vol.23 No.10, 1989
[Author] Takara, et al.
[Target] human, whole body
Radiation damages
[Title]
“Shokubutsu hakko sanbutsu no X-sen shosha ni taisuru bougyo kouka – shocho no senka saisei ni ataeru eikyo”
(The defensive effects of a fermented vegetable product on X-ray exposure – effects on the regeneration of intestinal crypts)
[Journal] The Journal of Japan Mibyo System Association Vol.12 No.1, 2006
[Author] Ashida, et al.
[Target] mouse, small intestine
Growth/Feedstuff
[Title]
Effect of Diet Supplemented with a Fermented Vegetable Product on Lipid Peroxidation in Liver of Japanese Flounder, Paralichthys olivaceus
[Journal] SUISANZOSHOKU 50(1), 2002
[Author] Ashida, et al.
[Target] flounder, liver
[Title]
Effects of fermented plant product on growth performance, some blood variables, carcase characteristics, and intestinal histology in broilers
[Journal] British Poultry Science Vol.53 No.2, 2012
[Author] Lokaewmanee, et al.
[Target] chicken, intestine, body weight